The One Spa Chicago

The One Spa Chicago offers: NAD+, IV Therapy, Myers Cocktail, Hydration, Vitamin C, Glutathione, Iron Infusion, B12 Shot, Hangover IV, Immune Boost, Weight Loss IV.

IV therapy at The One Spa Chicago ranges from $99.00 to $299.00 per session, depending on the infusion type. Basic hydration drips sit at the lower end while specialty treatments like NAD+ and glutathione run higher.

432 E Grand Ave Suite D, Chicago, IL 60611, Chicago, Illinois

Most IV therapy sessions at The One Spa Chicago take 30–60 minutes. Standard hydration and vitamin drips run 30–45 minutes; NAD+ infusions can take 2–4 hours depending on dose. Plan to arrive 10–15 minutes early for a brief intake on your first visit.

IV therapy at The One Spa Chicago is administered by licensed medical staff using sterile, single-use equipment. Most wellness IV drips operate under standing physician orders in Illinois, and prescription-grade infusions (NAD+, ketamine, high-dose vitamin C) require a brief consultation. Side effects are typically minor — bruising at the injection site or a cool sensation during the drip.

The One Spa Chicago accepts walk-ins, but appointments are recommended — especially for NAD+ and specialty infusions that require longer chair time. Call +1312-340-6740 to confirm same-day availability.

The One Spa Chicago operates as a clinic-based provider. For at-home service in Chicago, check the other 155 listings below — several Chicago clinics and national mobile providers (Drip Hydration, Mobile IV Medics) offer in-home drips.